1.AUD相关神经环路及神经核团病理机制研究 ；

2.脂质代谢紊乱调控神经系统疾病的病理机制研究

发表论文：

[1] Ren Z, Zhang C, Ma L, Zhang X, Shi S, Tang D, Xu J, Hu Y, Wang B, Zhang F, Zhang X^*, Zheng H^*. Lysophosphatidic acid induces the migration and invasion of SGC-7901 gastric cancer cells through the LPA2 and Notch signaling pathways [J]. International journal of molecular medicine, 2019, 44(1): 67-78.

[2] Ren Z, Hou J, Li W, Tang Y, Wang M, Ding R, Liu S, Fu Y, Mai Y, Xia J, Zuo W, Zhou L，Ye JH^*, Fu R^*. LPA1 receptors in the lateral habenula regulate negative affective states associated with alcohol withdrawal. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology 2023, 48(11): 1567-1578.

[3] Li W, Ren Z, Tang Y, Fu Y, Sun S, Ding R, Hou J, Mai Y, Zhan B, Zhu Y, Zuo W, Ye JH^*, Fu R^*. Rostromedial tegmental nucleus nociceptin/orphanin FQ (N/OFQ) signaling regulates anxiety- and depression-like behaviors in alcohol withdrawn rats [J]. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, 48(6): 908-19.（共同第一）

[4] Zhang X, Zhang C, Ren Z, Zhang F, Xu J, Zhang X^*, Zheng H^*. Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin. Cancer management and research. 2020; 12:3795-806.

[5] Fu R, Tang Y, Li W, Ren Z, Li D, Zheng J, Zuo W, Chen X, Zuo Q, Kelsey L, Zuo Y, Thomas B, Alex B, Ye JH^*. Endocannabinoid signaling in the lateral habenula regulates pain and alcohol consumption. Translational psychiatry 2021, 11(1): 220.

[6] Mi J, Yang Y, Yao H, Huan Z, Xu C, Ren Z, Li W, Tang Y, Fu R*, Ge X^*. Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway: HSPA8 inhibition protects spinal ischemia-reperfusion injury. Journal of neuroinflammation. 2021;18(1):170.

[7] Ding R, Tang Y, Cao G, Mai Y, Fu Y, Ren Z, Li W, Hou J, Sun S, Chen B, Han X, He Z, Ye JH^*, Zhou L^*, Fu R^*. Lateral habenula IL-10 controls GABA_A receptor trafficking and modulates depression susceptibility after maternal separation. Brain Behav Immun. 2024 Nov; 122:122-136.

[8] 任志恒,张晨丽,张晓,史淑霞,徐金宇, 张煦^*,胡燕,王斌生. γ-分泌酶抑制剂阻断LPA诱导的胃癌细胞SGC-7901侵袭迁移[J].临床与实验病理学杂志,2020,36(01):15-19.

主持的科研项目：

1.甘肃省青年科技基金项目（24JRRA450），2024.8-2026.7

2.中央高校基本科研业务费专项资金项目-自由探索项目（Lzujbky 20240030），2024.7-2026.6

学术交流：

1.中国解剖学会第 37 届学术年会，2023年7月21-23日，四川成都，发言交流

2.中华医学会病理学分会第二十九次学术会议暨第十三届病理年会，2024年3月28～31日，北京，壁报交流